Life ⚓️#
Conclusion: Is There a Solution?#
If there is a solution to the fundamental problem of navigating the world, it is this:
We do not control the ecosystem, but we can control our framing of it.
The key is not to eliminate cacophony but to transform it—to move from seeing the world as an assault to seeing it as a composition in which we are both performers and audience. Meaning is not something found; it is something imposed.
And so, the final act is to listen—to hear the noise of existence and discern in it a pattern, a structure, a symphony. The world does not grant coherence freely. But in our capacity to impose it, we create not just survival, but civilization.
Show code cell source
import numpy as np
import matplotlib.pyplot as plt
import networkx as nx
# Define the neural network layers
def define_layers():
return {
'Suis': ['DNA, RNA, 5%', 'Peptidoglycans, Lipoteichoics', 'Lipopolysaccharide', 'N-Formylmethionine', "Glucans, Chitin", 'Specific Antigens'],
'Voir': ['PRR & ILCs, 20%'],
'Choisis': ['CD8+, 50%', 'CD4+'],
'Deviens': ['TNF-α, IL-6, IFN-γ', 'PD-1 & CTLA-4', 'Tregs, IL-10, TGF-β, 20%'],
"M'èléve": ['Complement System', 'Platelet System', 'Granulocyte System', 'Innate Lymphoid Cells, 5%', 'Adaptive Lymphoid Cells']
}
# Assign colors to nodes
def assign_colors():
color_map = {
'yellow': ['PRR & ILCs, 20%'],
'paleturquoise': ['Specific Antigens', 'CD4+', 'Tregs, IL-10, TGF-β, 20%', 'Adaptive Lymphoid Cells'],
'lightgreen': ["Glucans, Chitin", 'PD-1 & CTLA-4', 'Platelet System', 'Innate Lymphoid Cells, 5%', 'Granulocyte System'],
'lightsalmon': ['Lipopolysaccharide', 'N-Formylmethionine', 'CD8+, 50%', 'TNF-α, IL-6, IFN-γ', 'Complement System'],
}
return {node: color for color, nodes in color_map.items() for node in nodes}
# Define edge weights
def define_edges():
return {
('DNA, RNA, 5%', 'PRR & ILCs, 20%'): '1/99',
('Peptidoglycans, Lipoteichoics', 'PRR & ILCs, 20%'): '5/95',
('Lipopolysaccharide', 'PRR & ILCs, 20%'): '20/80',
('N-Formylmethionine', 'PRR & ILCs, 20%'): '51/49',
("Glucans, Chitin", 'PRR & ILCs, 20%'): '80/20',
('Specific Antigens', 'PRR & ILCs, 20%'): '95/5',
('PRR & ILCs, 20%', 'CD8+, 50%'): '20/80',
('PRR & ILCs, 20%', 'CD4+'): '80/20',
('CD8+, 50%', 'TNF-α, IL-6, IFN-γ'): '49/51',
('CD8+, 50%', 'PD-1 & CTLA-4'): '80/20',
('CD8+, 50%', 'Tregs, IL-10, TGF-β, 20%'): '95/5',
('CD4+', 'TNF-α, IL-6, IFN-γ'): '5/95',
('CD4+', 'PD-1 & CTLA-4'): '20/80',
('CD4+', 'Tregs, IL-10, TGF-β, 20%'): '51/49',
('TNF-α, IL-6, IFN-γ', 'Complement System'): '80/20',
('TNF-α, IL-6, IFN-γ', 'Platelet System'): '85/15',
('TNF-α, IL-6, IFN-γ', 'Granulocyte System'): '90/10',
('TNF-α, IL-6, IFN-γ', 'Innate Lymphoid Cells, 5%'): '95/5',
('TNF-α, IL-6, IFN-γ', 'Adaptive Lymphoid Cells'): '99/1',
('PD-1 & CTLA-4', 'Complement System'): '1/9',
('PD-1 & CTLA-4', 'Platelet System'): '1/8',
('PD-1 & CTLA-4', 'Granulocyte System'): '1/7',
('PD-1 & CTLA-4', 'Innate Lymphoid Cells, 5%'): '1/6',
('PD-1 & CTLA-4', 'Adaptive Lymphoid Cells'): '1/5',
('Tregs, IL-10, TGF-β, 20%', 'Complement System'): '1/99',
('Tregs, IL-10, TGF-β, 20%', 'Platelet System'): '5/95',
('Tregs, IL-10, TGF-β, 20%', 'Granulocyte System'): '10/90',
('Tregs, IL-10, TGF-β, 20%', 'Innate Lymphoid Cells, 5%'): '15/85',
('Tregs, IL-10, TGF-β, 20%', 'Adaptive Lymphoid Cells'): '20/80'
}
# Define edges to be highlighted in black
def define_black_edges():
return {
('Lipopolysaccharide', 'PRR & ILCs, 20%'): '20/80',
('N-Formylmethionine', 'PRR & ILCs, 20%'): '51/49',
("Glucans, Chitin", 'PRR & ILCs, 20%'): '80/20',
('Specific Antigens', 'PRR & ILCs, 20%'): '95/5',
('PRR & ILCs, 20%', 'CD8+, 50%'): '20/80',
('PRR & ILCs, 20%', 'CD4+'): '80/20',
('CD4+', 'TNF-α, IL-6, IFN-γ'): '5/95',
('CD8+, 50%', 'TNF-α, IL-6, IFN-γ'): '49/51',
}
# Calculate node positions
def calculate_positions(layer, x_offset):
y_positions = np.linspace(-len(layer) / 2, len(layer) / 2, len(layer))
return [(x_offset, y) for y in y_positions]
# Create and visualize the neural network graph
def visualize_nn():
layers = define_layers()
colors = assign_colors()
edges = define_edges()
black_edges = define_black_edges()
G = nx.DiGraph()
pos = {}
node_colors = []
# Create mapping from original node names to numbered labels
mapping = {}
counter = 1
for layer in layers.values():
for node in layer:
mapping[node] = f"{counter}. {node}"
counter += 1
# Add nodes with new numbered labels and assign positions
for i, (layer_name, nodes) in enumerate(layers.items()):
positions = calculate_positions(nodes, x_offset=i * 2)
for node, position in zip(nodes, positions):
new_node = mapping[node]
G.add_node(new_node, layer=layer_name)
pos[new_node] = position
node_colors.append(colors.get(node, 'lightgray'))
# Add edges with updated node labels
edge_colors = []
for (source, target), weight in edges.items():
if source in mapping and target in mapping:
new_source = mapping[source]
new_target = mapping[target]
G.add_edge(new_source, new_target, weight=weight)
edge_colors.append('black' if (source, target) in black_edges else 'lightgrey')
# Draw the graph
plt.figure(figsize=(12, 8))
edges_labels = {(u, v): d["weight"] for u, v, d in G.edges(data=True)}
nx.draw(
G, pos, with_labels=True, node_color=node_colors, edge_color=edge_colors,
node_size=3000, font_size=9, connectionstyle="arc3,rad=0.2"
)
nx.draw_networkx_edge_labels(G, pos, edge_labels=edges_labels, font_size=8)
plt.title("OPRAH™: Dorsal", fontsize=18)
plt.show()
# Run the visualization
visualize_nn()


Fig. 6 Innovation: Veni-Vidi, Veni-Vidi-Vici. If you’re protesting then you’re not running fast enough. Thus spake the Red Queens#