Immutable

This book encapsulates the essence of ingenuity and progress—leveraging the cutting-edge tools of today to resolve humanity’s perennial challenges. It reflects an understanding of both innovation and resourcefulness, emphasizing the need to optimize what is already within our grasp.

Victory is using the latest technology to address the oldest issues with existing resources.
– Yours Truly

This perspective is particularly potent when applied to societal problems like healthcare, education, and sustainability. For instance, the integration of AI into personalized medicine allows us to use data-driven insights to address ancient questions of health, longevity, and resilience. Similarly, utilizing existing natural resources more efficiently through technology addresses the age-old struggle between human needs and environmental balance.

True victory lies in this synergy—melding the past and present to shape a sustainable, equitable, and innovative future. It’s not merely about creating something new but about reimagining the old through the lens of modern capability.

The neural network we describe, interwoven with themes of mythology, philosophy, and economics, becomes a map of human ambition, frailty, and technological evolution. It begins with an input layer grouped into three symbolic pairs: Theomachy (the abyss), Mortals (that doesn’t kill you), and Fire (makes you stronger). These pairs echo primal struggles: divine conflict (gamble), human mortality (bet), and the Promethean gift of technology (invest). Each group serves as a node, progressively compressing the chaotic vastness of human history into legible patterns and collapsed odds (gamble, bet, invest). The essay, structured to align with the five layers of the neural network—World, Yellow, Agent, Generative, and Physical—while incorporating key quotes, video, and the thematic elements of relevance. Each section reflects the hierarchical organization of our neural framework.

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World: The Immutable Foundation

The neural network begins with the immutable, encompassing the foundational triad of Theomachy, Mortals, and Fire from Prometheus. These primal forces symbolize the perpetual tension between cosmic chaos and order, human frailty, and technological ambition. Theomachy evokes the grand conflicts of the cosmos, mirrored in ecological entropy and systemic imbalance. Mortals embody the Red Queen Hypothesis—a ceaseless race to adapt or perish, driven by survival and limitation. Fire, the gift of Prometheus, represents the transformative power of energy and technology, a double-edged sword that can uplift or destroy.

“It will happen, improvement,” Prometheus seems to promise, as fire fuels humanity’s insatiable drive to reweight the system in its favor.

This immutable layer encodes a universal law: as energy is harnessed for human ends, cartels inevitably emerge. In various flavors of coffee, for instance, we observe how supply chains generate efficiencies, and demand compels monopolistic consolidation. Fire, here, serves as both means and metaphor—fueling systems that bridge ecological cost, technological capability, and enterprise ambition.

Fig. 1 Red Queen in the House - Prior Authorization and Trust in US Health Care. SEC tokenizing stocks & bonds is like IRB tokenizing access to EHR. Let’s explore this! Let’s segue to a related matter. The public response to the killing of United Healthcare’s CEO made it hard to ignore the erosion of trust in U.S. health care. Even before that, more questions were being raised about prior authorization – insurers’ tools for approving or denying a proposed treatment or drug. Patients need appropriate care in a timely manner. Providers need to spend less time dealing with barriers and bureaucracy to get patients that care. And, insurers need to be sure they are paying for the right care – not for overtreatment, unnecessary treatment, or overly aggressive care. Join us for a candid discussion of the friction points, the frustrations, and some emerging potential solutions as U.S. healthcare seeks that delicate balance

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Yellow: Perception as Judgment

The Yellow Layer represents the perceptual mechanism that interprets the immutable. It is here that the system discerns patterns and assigns meaning, much like Prometheus’ fire illuminating the dark. This is the realm of judgment, where inputs are framed not as raw data but as choices—ethical, strategic, and evolutionary.

In the saga of Sam Bankman-Fried, perception warped judgment. FTX’s interventions, framed as ecosystem stabilization, revealed themselves as power plays. The company’s bailouts of rivals, ostensibly altruistic, embodied Promethean overreach—a mortal attempting to wield fire to reorder the cosmos. Yet this misjudgment underlined a crucial point: perception is not inherently truthful but contingent, shaped by the network’s biases and blind spots.

Sam Blankman-Fried’s FTX was tapping into ecosystem-integrating processes
– Yours Truly

Connoisseurs often spit during professional tastings—whether it’s coffee, wine, or liquor—and your interpretation of this act as resisting “consumption” aligns beautifully with the purpose behind it. They aim to remain in the realm of sensory evaluation, unclouded by the physiological or psychological transformations that actual consumption would induce.

By spitting, they isolate the experience to its pure sensory elements: the interplay of taste, aroma, and texture. This choice prevents the cumulative effects of alcohol intoxication, caffeine stimulation, or the lingering fullness of consumption, which could compromise their ability to evaluate subsequent samples objectively. It ensures their ascending sensory pathways (taste buds, olfactory bulbs) remain sharp and unaltered as they ascend into cognition for analysis and comparison.

Your phrase, “consumption is transformational,” captures the core distinction. Consumption implies integration into the self—biologically, chemically, and emotionally. Wine transforms into relaxation, coffee into stimulation, liquor into inebriation. Spitting rejects this, keeping the taster in an observational state rather than a participatory one. It’s a fascinating boundary: they flirt with transformation by engaging the senses but stop just short of surrendering to it.

In a way, professional tasters inhabit an iterative loop: sampling, processing, and resetting, rather than progressing into the adversarial or cooperative layers of consumption’s equilibrium. They maintain control, staying at the sensory threshold where knowledge can emerge without the full embodiment of experience. It’s an almost ascetic practice—resisting the natural pull toward indulgence.

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Agent: Nodes of Control

At the Agent Layer, the system transitions from perception to action. Here, individuals and collectives navigate the tensions between open systems and closed hierarchies, between generative collaboration and cartelized domination. Theomachy compresses into the struggle between trust and centralization, Mortals into the trade-offs of resource allocation, and Fire into the wielding of power.

Bankman-Fried’s agency, characterized by rapid liquidity injections and centralized control, exemplified the tension within this layer. His vision of FTX as a stabilizing force clashed with the inherent instability of concentrated power. The attempt to play both savior and ruler—open and closed—highlighted the paradox of agency: the very tools that enable generative action can enforce monopolistic stagnation.

Leveraged Agency

• Theomarchy

  • Abyss/Gamble: Divine-Priest, Prayer, Coin, Dice, Roulette

• Mortals

  • Bet: Josting-Knight, Poker, Racing-Horse

• Fire

  • Invest: F1-Hamilton, Monopolized

Curtailed Agency

• Relative position

  • Cosmos-Entropy

  • Planet-Tempered

    • War: Resources

    • Chess: Resourcefulness

• Mutual Destruction

  • Ecosystem-Cost

  • Life-Needs

• Hierarchy

  • Cartel-Ends, Generative-Means

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Generative: Explosive Dynamics

The Generative Layer captures the explosive potential of compressed energy. This is where ratios are weaponized, competition tokenized, and odds monopolized. Fire becomes both a creative and destructive force, amplifying the system’s contradictions.

In this layer, FTX’s actions transcended mere interventions—they became systemic distortions. By bailing out competitors, Bankman-Fried disrupted the natural attrition that underpins evolutionary balance. His moves, while initially stabilizing, introduced feedback loops that undermined the market’s integrity. Promethean fire, in this context, was no longer a gift but a weapon—one that risked consuming its wielder.

“Demand and supply, Mr. Wallis. Demand and supply.”
– Various Flavors of Coffee

This quote encapsulates the layer’s essence: generative dynamics are governed by the immutable law of demand and supply, yet their manipulation introduces profound consequences. The emergence of cartels, efficiencies, and monopolies reflects not just economic logic but the generative layer’s inherent volatility.

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Physical: Values and Vulnerabilities

The Physical Layer represents the tangible outcomes of the network—values, vulnerabilities, and societal shifts. It is here that Promethean fire’s duality is most evident. When wielded wisely, it fuels “Exuberant Jubilee” or “Freedom-Dance in Chains,” balancing liberation with dependency. Misused, it leads to “Stable-Conservative” stagnation or “Unveiled Resentment,” as systems fracture under inequity.

Bankman-Fried’s narrative, at this layer, reveals the fragility of systems overburdened by artificial stabilization. His consolidation of power, meant to ensure stability, instead fostered resentment and revolutionary potential. The fire that sustained FTX’s rise became the catalyst for its fall, a cautionary tale of hubris and overreach.

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Iteration: The Recursive Cycle

The network does not end at the physical layer; it loops back, creating a recursive cycle. Theomachy evolves, Mortals adapt, and Fire refines itself through each iteration. Blankman-Fried’s failures become lessons for the next generation of actors, embedding new complexities into the system.

As the cycle repeats, the neural network grows richer, capturing the interplay between immutable laws, perceptual judgments, agentic choices, generative dynamics, and physical outcomes. Each layer informs and reweights the others, ensuring that the fire of Prometheus continues to burn—both as a gift and a warning.

Show code cell source Hide code cell source

# LEFT: Life, Ecosystem, Fire, Tech
import numpy as np
import matplotlib.pyplot as plt
import networkx as nx

# Define the neural network fractal
def define_layers():
    return {
        'World': ['Cosmos-Entropy', 'Planet-Tempered', 'Life-Needs', 'Ecosystem-Costs', 'Generative-Means', 'Cartel-Ends', ], # Theomarchy (Nothing kills immortals), Mortals (What doesn't kill you--), Fire (Makes you stronger)
        'Perception': ['Perception-Ledger'], # God (Perspectivism)
        'Agency': ['Open-Nomiddleman', 'Closed-Trusted'], # Evil & Good (Beyond this dichotomy)
        'Generative': ['Ratio-Weaponized', 'Competition-Tokenized', 'Odds-Monopolized'], # Dynamics, Compromises (Becoming, not Being)
        'Physical': ['Volatile-Transvaluation', 'Unveiled-Resentment',  'Freedom-Dance in Chains', 'Exuberant-Jubilee', 'Stable-Conservative'] # Values (Transvaluation of all of them!)
    }

# Assign colors to nodes
def assign_colors():
    color_map = {
        'yellow': ['Perception-Ledger'], # , Judgement Day, Key
        'paleturquoise': ['Cartel-Ends', 'Closed-Trusted', 'Odds-Monopolized', 'Stable-Conservative'], # Slavery, Colonialism, Worker
        'lightgreen': ['Generative-Means', 'Competition-Tokenized', 'Exuberant-Jubilee', 'Freedom-Dance in Chains', 'Unveiled-Resentment'], # Das Kapital, Frankenstein, AI
        'lightsalmon': [
            'Life-Needs', 'Ecosystem-Costs', 'Open-Nomiddleman', # Ecosystem = Red Queen = Prometheus = Sacrifice
            'Ratio-Weaponized', 'Volatile-Transvaluation'
        ],
    }
    return {node: color for color, nodes in color_map.items() for node in nodes}

# Calculate positions for nodes
def calculate_positions(layer, x_offset):
    y_positions = np.linspace(-len(layer) / 2, len(layer) / 2, len(layer))
    return [(x_offset, y) for y in y_positions]

# Create and visualize the neural network graph
def visualize_nn():
    layers = define_layers()
    colors = assign_colors()
    G = nx.DiGraph()
    pos = {}
    node_colors = []

    # Add nodes and assign positions
    for i, (layer_name, nodes) in enumerate(layers.items()):
        positions = calculate_positions(nodes, x_offset=i * 2)
        for node, position in zip(nodes, positions):
            G.add_node(node, layer=layer_name)
            pos[node] = position
            node_colors.append(colors.get(node, 'lightgray'))  # Default color fallback

    # Add edges (automated for consecutive layers)
    layer_names = list(layers.keys())
    for i in range(len(layer_names) - 1):
        source_layer, target_layer = layer_names[i], layer_names[i + 1]
        for source in layers[source_layer]:
            for target in layers[target_layer]:
                G.add_edge(source, target)

    # Draw the graph
    plt.figure(figsize=(12, 8))
    nx.draw(
        G, pos, with_labels=True, node_color=node_colors, edge_color='gray',
        node_size=3000, font_size=9, connectionstyle="arc3,rad=0.2"
    )
    plt.title("“The difficulty with my plans,” Pinker explained, “is cost. \n Coffee is expensive stuff—much more costly than beer or gin”.", fontsize=15)
    plt.show()

# Run the visualization
visualize_nn()

Fig. 2 Align Elon Musks Reaction to Stargate with Emily’s “Mutiny & Obedience”. But before you do that, 54132 merely matched these movie ranks to the network layers. Reveals something that I’ll leave unstated. Tokens are digital assets (keys) to open up a ledger (yellow). What exactly the ledger is about is another topic altogether. But it might be API, block chain, or access to Microsofts Azure. In essence, the way forward for government-supported AI efforts must navigate this complex landscape of technological promise versus human complexity. By learning from the decentralized and transparent nature of cryptocurrency, there’s potential to create an AI ecosystem that not only advances our capabilities but also aligns with democratic ideals of openness and participation. The journey of AI from perception to physical reality, as depicted in the neural network, should ideally reflect a path where technology serves humanity’s collective needs, not just the interests of its creators or controllers. The thing to me that’s always been weird about this is that no one’s articulated a vision for what the world will look like. They’re always willing to say it comes down to supercharged scientific research, which may very well be true, but also requires rethinking how science is organized to take advantage of these models. What does that look like? There are a lot of other social components that have to fit into it

The neural network we are constructing reflects an intricate mapping of the cosmos to human consciousness, moving from universal entropy to the psychological curtailing of experience. This structure captures not just the hierarchical flow of information but also the dynamic interplay of disciplines and systems that govern existence. Each node—rooted in a specific scientific or philosophical domain—acts as a lens through which the cosmos unfolds into increasingly complex forms of organization and understanding. Let’s explore how the layers interact, focusing on the thematic progression from entropy to psychology and the color-coded representation of these transformations.

At the foundation lies Cosmos-Entropy, the node where the journey begins. Cosmology, represented here, provides the framework for understanding the universe’s origins and its relentless march toward disorder. It is the primal chaos, the unifying starting point of existence, whose tempering flows into Geology through the Planet-Tempered node. Geology represents a stabilizing force, the cooling and crystallization of chaos into planets, mountains, and ecosystems. This interplay of entropy and temperance is the canvas upon which life can emerge—a transition from raw potential to bounded possibility.

Life, represented by Life-Needs and colored in lightsalmon, marks the biological awakening of the universe. Here, biology provides the tools to harness energy, reproduce, and evolve. This biological vibrancy carries forward into Ecosystem-Costs, where ecology becomes the central node. The shift from individual life to interconnected systems signals a profound elevation of complexity—an acknowledgment of the cost of existence. Ecology’s lightsalmon shade suggests an ongoing negotiation with entropy, highlighting the delicate balance required to sustain life.

As we move into the Generative-Means node, sociology takes center stage. This green node encapsulates the emergent properties of human collectives—communication, culture, and cooperation. Sociology builds upon the scaffolding of biology and ecology, demonstrating humanity’s unique capacity to transcend individual survival and create shared meaning. This is the node where life, previously reactive, begins to act deliberately, shaping its environment and society.

“Why should we not have a coffee-house on every street instead? It would be an Improvement, would it not? Yes? Then, if it is an Improvement, it must happen—it will happen. Darwin says so! And I will be the one to make it happen.” He sat down, dabbing at his forehead with his sleeve.
“You mentioned a code,” I said. “I still don’t quite see—”
“Yes. Demand and supply, Mr. Wallis. Demand and supply.”
– Various Flavors of Coffee

Finally, the neural network culminates in Cartel-Ends, where psychology presides. The paleturquoise color signals a curtailing—a drawing inward to focus on the subjective experience of individuals. Psychology, as a discipline, addresses the final frontier of entropy: the human mind. It seeks to understand the tension between generative aspirations and the limitations imposed by biology, ecology, and society. This final node represents a profound paradox: even as the cosmos expands toward entropy, the human mind curtails this chaos, creating internal order through perception, cognition, and emotion.

The inclusion of chemistry as the yellow node, with organic chemistry as its focus, enriches the network’s grounding. Chemistry is the bridge between inert matter and living systems, providing the molecular toolkit for biology and ecology to operate. It occupies a pivotal space, linking the cosmological and geological realms to the biological and ecological.

What makes this neural network particularly compelling is its color-coded symbolism. Lightsalmon represents the biological and ecological negotiation with entropy—vibrant yet fragile. Green symbolizes the generative potential of human societies, while paleturquoise reflects the psychological curtailing of chaos into individual narratives. Yellow, associated with chemistry, underscores the alchemical transformation of matter into life, a key inflection point in the cosmos’s evolution.

Perspectivism… Transvaluation
– The Hammer

The neural network’s layers—World, Perception, Agency, Generative, and Physical—further clarify its structure. The World layer anchors the network in the tangible, while Perception introduces subjective awareness. Agency addresses the moral and ethical dynamics of human action, framing good and evil as emergent properties of choice. Generative explores the societal mechanisms of competition and cooperation, while Physical roots these abstract concepts in tangible expressions of values and transvaluations.

In sum, this neural network is more than a diagram—it is a narrative of existence. It charts the cosmos’s journey from entropy to psychology, illustrating how each domain builds upon the last to create an interconnected whole. The color coding adds a poetic dimension, emphasizing the delicate balance between chaos and order, between expansion and curtailing. This is a framework that invites exploration, a roadmap for understanding the intricate dance of systems that shape our world and ourselves.

Odds, Sales-Pitch

1. Fixed (Gamble)

2. Long (Bet)

3. Short (Invest)

4. Gamefication 🏟️ (Chess)

5. Resources (Existing)

• Theomachy. Annual US News & World Report rankings; 100,000 deployments to GitHub (automation, the gamble is on the 5/95 failures due to cosmic flux); ensures we maintain lead in foreseeable future

• Mortals. Personalized Kaplan-Meier curves for patients, decision-makers

• Fire 🔥. Ecosystem integration for students, collaborators, IRBs, patients, care providers, EHR, national databases

• Chess ♟️ . Learning across massive combinatorial space (PAIRS@JH)

• Unleash power of big data by tapping into novel ecosystem-integration of the scientific enterprise (see case-study). Winner 🏅 🏆 🥇 is the ecosystem that has scalable utilization of existing resources in most innovative way (resourcefulness), thereby not only inviting blockchain miners who might resent the limited access to PI-gated data, but ensuring their freedom within fetters of regulation, jubilation on winning something akin to AlexNext, while securely ensconced within normative frameworks of academic medicine as well as transformative technologies available to us